The importance of Adverse Drug Event Reporting (ADE) system lies in its objective which is ,the provision of drug safety data to FMHACA pharmacovigilance center .This initial information enriched by further investigation will finally enable the users to prevent the recurrence of the adverse drug event in other patients resulting in the delivery of a better safe and quality health care. Frehiwot Zerihun Previously, I didn’t know about the ADE reporting system, and the allergy card. But one day I shared the idea from other health center. Now ,when i get ADEs ,I report quickly because by the feedbacks i am receiving from FMHACA, i now understand that my participation in the system will add more knowledge about the effect of drugs, save my clients from drug related injuries and i will also be involved in the reduction of drug resistance.